首先我们来看下despite和despite of和in spite of的大致意思：
despite：词性为介词，Despite the rain, we still went for a walk in the park.
despite of：词性为介词短语，Despite of the bad weather, they still went camping.
in spite of：词性为介词短语，In spite of the traffic jam, she arrived on time.
通过下面的表格我们了解下despite和despite of和in spite of的含义、发音和用法
接下来让我们看下despite和despite of和in spite of的用法区别：
🚀🚀🚀 despite 🚀🚀🚀
用法详解：后接名词或动名词
例子：
- Despite the rain, we still went for a walk in the park.
(尽管有雨，我们依然去了公园散步。)
用法详解：可以使用in spite of作为替代
例子：
- In spite of being tired, he worked all night.
(尽管他很累，但他坚持工作了整个晚上。)
用法详解：可以用于句首、句中或句尾
例子：
- Despite her young age, she has achieved a lot.
(尽管她年纪轻，但她的成就已经非常了不起了。)
🚀🚀🚀 despite of 🚀🚀🚀
用法详解：后接名词或动名词
例子：
- Despite of the bad weather, they still went camping.
(尽管天气不好，他们还是去野营了。)
用法详解：较少使用，通常建议使用despite
例子：
- Despite of his hard studying, he still didn't pass the exam.
(尽管他努力学习，但他仍然没通过考试。)
用法详解：在正式写作和正式场合中不常见
例子：
- Despite of his wealth, he is still not happy.
(尽管他有钱，他仍然没有快乐。)
🚀🚀🚀 in spite of 🚀🚀🚀
用法详解：后接名词或动名词
例子：
- In spite of the traffic jam, she arrived on time.
(尽管遇到交通堵塞，她还是准时到达了。)
用法详解：较常用于正式写作和正式场合
例子：
- In spite of his calm appearance, he was very worried inside.
(尽管他表面冷静，但他内心非常担心。)
用法详解：可以使用despite作为替代
例子：
- Despite the many doubts from the outside, he still firmly believes in his ideas.
(尽管外界有很多质疑，他依然坚信自己的理念。)