如何在Genbank上查找某一生物表达特定蛋白的一段基因序列？

Question

我想找链霉菌表达脂肪酶的基因。

Answer 1

直接在NCBI主页输入你要找的基因的名字，比如S1PR1，然后搜索，找到下面的内容:

Genes

90Gene: collected information about gene loci

1HomoloGene: homologous gene sets for selected organisms

12UniGene: clusters of expressed transcripts

点90进去，里面是NCBI上这个基因在不同物种中的所有序列，找到是链霉菌这个物种就ok，我如果找人的话，就应该是:
S1PR1 – sphingosine-1-phosphate receptor 1 [Homo sapiens (human)]

Answer 2

直接在NCBI主页输入你要找的基因的名字，比如S1PR1，然后搜索，找到下面的内容：
Genes
90Gene: collected information about gene loci
1HomoloGene: homologous gene sets for selected organisms
12UniGene: clusters of expressed transcripts

点90进去，里面是NCBI上这个基因在不同物种中的所有序列，找到是链霉菌这个物种就ok，我如果找人的话，就应该是：
S1PR1 – sphingosine-1-phosphate receptor 1 [Homo sapiens (human)]

然后再点进去
Genomic
NG_016181.1 RefSeqGene
Range
5001..9772
Download
GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
NM_001400.4 → NP_001391.2 sphingosine 1-phosphate receptor 1
See proteins identical to NP_001391.2
Status: REVIEWED
pfam00001
Location:68 – 311
Blast Score: 367
7tm_1; 7 transmembrane receptor (rhodopsin family)
Source sequence(s)
BC018650, CR977007, DB132417, DB572979
Consensus CDS
CCDS777.1
UniProtKB/Swiss-Prot
P21453
Related
ENSP00000305416, OTTHUMP00000012525, ENST00000305352, OTTHUMT00000029908
Conserved Domains (1) summary

GenBank和FASTA可以查看它在基因组上的序列
NM_001400.4 和 NP_001391.2分别是其mRNA序列和蛋白质序列

祝好！